Wayne traveled to Quebec for Anik's "boch et biche" party, along with a large contingent of Letterkenny townsfolk, to help defend it against degens from Laval. The old French man selling tickets at the door told Wayne he wanted to introduce his niece to him, as she had been unlucky in love; when Marie-Fred arrived later in the evening, she and Wayne fall in love at first sight ("Bock et Biche").
They began a long-distance relationship, taking turns to drive to each other on the weekends, which landed Wayne in scraps with locals and landed Marie-Fred a number of speeding tickets. They also suffer indignities owing to prejudices the English Canadians have against the French and vice versa ("What Could Be So Urgent?"). Around the same time, Anik and Daryl begin dating, and she and Anik become frequent visitors to town, spending time with their sweethearts at the farm and working out together at the gym.
Anik eventually breaks up with Daryl. Wayne, meanwhile, is busy making financial arrangements—to buy a ring ("Yew!").
Marie-Fred first meets Wayne at Anik's "bock et biche"; when he sees her at the entrance, it is love at first sight ("Bock et Biche"). Despite the long distance, they carry on an active romance, becoming quite close.
Overall, Marie-Fred and Wayne appear to be very compatible, sharing a similar outlook on life and similar senses of humour. Marie-Fred gets along well with the other Hicks, and though she endures some indignities from some other locals when visiting, she is welcomed warmly by others, and happily takes part in local traditions like Century Club ("Different Strokes for Different Folks"). They also enjoy an enviable sex life ("Bush Party Season"). Although she is not yet aware, Wayne plans to propose to her ("Yew!").
It is revealed in the Season 7 finale that she is cheating on Wayne.
Marie-Fred has presumably been friends with Anik for some time, as Anik was engaged to her brother Jean-Claude. They remain friends after Anik breaks up with Jean-Claude, who is never mentioned in their subsequent conversations, and they make trips to Letterkenny together after Anik begins dating Daryl. In Letterkenny, they spend time together at the farm and working out together at the gym, where they have very frank conversations about their sex lives ("Bush Party Season").
Jean-Claude is protective of his sister Marie-Fred, but their relationship is complicated when Anik breaks up with him and Marie-Fred begins dating Wayne. Jean-Claude dislikes the English in general—disallowing Anik from inviting her English family to their later-canceled wedding—and is suspicious and resentful of Wayne ("Bock et Biche"). He and his cousin Jean-Lance try to undermine Wayne, for example, by accosting the couple at a restaurant and mocking his French pronunciation ("What Could Be So Urgent?"). Marie-Fred is impatient with this behaviour, but does nothing to stop it besides saying "Jean-Claude" in a scolding voice.
- ("Bock et Biche")
- ("What Could Be So Urgent?")
- ("Bush Party Season")
- ("Dyck's Slip Out")
- ("Different Strokes for Different Folks")